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Pharmaceutical Steroid Exemestane Aromasin For Antitumor CAS 107868-30-4

Jinan  Jia  Ge  Biological  Technology  Co., Ltd.

Province/State:shandong

Country/Region:china

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Pharmaceutical Steroid Exemestane Aromasin For Antitumor CAS 107868-30-4

Brand Name : JNJG
Model Number : 107868-30-4
Certification : USP BP SGS KOSHER
Place of Origin : CHINA
MOQ : 10g
Price : negotiation
Payment Terms : TT, Money Gram, Western Union, Bitcoin
Supply Ability : 500kg/per week
Delivery Time : within 12 hours after you payment
Packaging Details : 1kg/ foil bag or as your requirement
CAS : 107868-30-4
Synonym : Aromasin; Exemestan
MF : C20H24O2
MW : 296.4
Appearance : White crystalline powder
Use : used to fight breast cancer
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Pharmaceutical Steroid Exemestane Aromasin For Antitumor CAS 107868-30-4


Quick Detail

Product Name

Exemestane


Synonym

Aromasin;Exemestan;Exemestane


CAS

107868-30-4


MF

C20H24O2


MW

296.4


Melting Point

155.13°C


Solubility

DMSO: ≥20mg/mL


Appearance

White crystalline powder


Standard

Enterprise Standard


Certification

ISO9001, UPS


Usage

Aromasin is used to fight breast cancer and raise testosterone in the body



Description


Exemestane is an aromatase inhibitor. This means it blocks the enzyme aromatase (found in the body's muscle, skin, breast and fat), which is used to convert androgens (hormones produced by the adrenal glands) into estrogen. In the absence of estrogen, tumors dependent on this hormone for growth will shrink.


Exemestanes Aromasin is an irreversible, steroidal aromatase inactivator, structurally related to the natural substrate androstenedione. It acts as a false substrate for the aromatase enzyme, and is processed to an intermediate that binds irreversibly to the active site of the enzyme causing its

inactivation, an effect also known as "suicide inhibition." By being structurally similar to enzyme targets, Exemestanes Aromasin permanently binds to the enzymes, preventing them from converting androgen into estrogen.



Application


Aromasin is used to fight breast cancer and raise testosterone in the body.

Exemestane blocks the process of aromatisation. So it lowers the amount of oestrogen in the body. In early breast cancer, taking exemestane can help to stop breast cancer coming back. In advanced breast cancer the cancer cells may grow more slowly or stop growing completely.


Exemestane (Aromasin) is a drug used to treat breast cancer. It is a member of the class of drugs known as aromatase inhibitors. Some breast cancers require estrogen to grow. Those cancers have estrogen receptors (ERs), and are called ER-positive. They may also be called estrogen-responsive, hormonally-responsive, or hormone-receptor-positive. Aromatase is an enzyme that synthesizes estrogen. Aromatase inhibitors block the synthesis of estrogen. This lowers the estrogen level, and slows the growth of cancers.


Specification

ItemSpecification

Result


DescriptionWhite Crystalline Powder

White Powder


IdentificationPositive

Positive


Assay(by HPLC)98.0~102.0%

98.64%


Absorbance(E1cm)465~495

482.5


Melting Point191~195°C

193.5~195.0°C


Loss On Drying0.5%max

0.19%


Specific Rotation+288°~ +298°

+290.2°


Residue On Ignition0.1%max

0.03%


Related SubstancesTotal:1.5%max

<1.3%


Single:0.5%max

<0.4%


Residue Solvents0.2%max

0.10%


Heavy Metals20PPm max

<10PPm



Dosage


This is dependent on the individual and, also, the amount of aromatizing compounds the person is running. Generally, a good starting dose is 12.5mg ED (every day) or 25mg EOD (every other day). The user must utilize blood work to see how their body is reacting at the starting dosage they choose and then adjust as needed. Experienced anabolic steroid users will usually find a dose they like and stick to it with no problems. As I said already, if you start noticing joint issues then the dose should be lowered; on the other hand, if you start noticing any estrogen related sides, such as puffy or sensitive breasts or water retention, it's time to increase the dosage.


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3)High quality,competitive price,fast delivery ,first-class service gain the trust and praise from the customers.


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